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:: Volume 3, Issue 1 And 2 (5-2016) ::
vacres 2016, 3(1 And 2): 1-4 Back to browse issues page
New insight into the application of outer membrane vesicles of Gram-negative bacteria
A Fateh, F Vaziri, F Rahimi Janani, S Ahmadi Badi, M Ghazanfari, M Davari, A Arsang, SD Siadat *
Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran. Tehran, Iran, Microbiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran
Abstract:   (6043 Views)

This review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (OMVs), originating from the surface of Gram negative bacteria including their outer membrane proteins and lipopolysaccharides. Moreover, the functional roles and applications of OMVs in medical research such as OMV-based vaccines, OMV adjuvants properties, OMV carriers in conjugated vaccines as well as in drug vehicles and delivery systems are discussed. Finally, new applications of these macromolecules as biotechnological tools are briefly presented.

Keywords: OMV, vaccine, drug vehicles, delivery systems.
Full-Text [PDF 222 kb]   (2475 Downloads)    
Type of Study: Original article |
Received: 2016/07/25 | Accepted: 2016/07/25 | Published: 2016/07/25
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Fateh A, Vaziri F, Rahimi Janani F, Ahmadi Badi S, Ghazanfari M, Davari M, et al . New insight into the application of outer membrane vesicles of Gram-negative bacteria. vacres. 2016; 3 (1 and 2) :1-4
URL: http://vacres.pasteur.ac.ir/article-1-77-en.html


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