چکیده: (19 مشاهده)
Protracted conflicts and sanctions impose sustained constraints on health systems, particularly vaccine supply chains and routine immunization services. This commentary examines domestic vaccine production as a resilience strategy under such conditions, using Iran as a case study in the Eastern Mediterranean Region (EMR). Drawing on publicly available global and regional immunization data, policy reports, and institutional documentation, the analysis explores how domestic manufacturing can serve as a governance instrument in conflict-affected and sanction-constrained settings. Framed within health governance and system-resilience perspectives—particularly the adaptive resilience model (emphasizing flexibility and continuity under ongoing stress)—it highlights Iran's sustained production of essential childhood vaccines, which has supported national coverage despite external pressures. However, governance gaps—including regulatory alignment, limited regional integration, and restricted access to international quality-assurance mechanisms—limit its broader potential. Four policy considerations are proposed to enhance resilience: regulatory convergence, pharmacovigilance strengthening, health diplomacy, and integration into national/EMR planning.