TY - JOUR T1 - Lactococcus lactis as a live delivery vector TT - JF - vacres JO - vacres VL - 3 IS - 3 UR - http://vacres.pasteur.ac.ir/article-1-88-en.html Y1 - 2016 SP - 39 EP - 43 KW - Lactococcus lactis KW - Live vector KW - Live delivery vaccines KW - Mucosal vaccines. N2 - Mucosal surfaces of the body provide a universal entry portal for all known and emerging infectious pathogenic microbes. Therefore, it seems that special vaccination strategies are needed for vaccines that can hinder the entry capability of pathogenic microbes through the mucosal surfaces. Lactic acid bacteria are widely used in the food industry and are presently applied as delivery vehicles in many biological investigations. Among these bacteria, Lactococcus lactis is considered as a promising candidate for mucosal live vaccines to be used as an antigen delivery vector. This is an attractive alternative and a safer vaccination strategy against the pathogens, compared to other conventional methods. In this review, we summarized the applications of L. lactis as a mucosal vector of vaccine delivery for heterologous expression of proteins and its applications in biotechnology. M3 10.18869/acadpub.vacres.3.7.1 ER -