دوره 8، شماره 1 - ( 4-1400 )                   جلد 8 شماره 1 صفحات 59-52 | برگشت به فهرست نسخه ها


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Hozouri H, Shamsian A, Aghasadeghi M, Doroud D. Comparative Study of AEFI of Hepatitis B Vaccine between Iran Ministry of Health CDC and VAERS Data during 2015 to 2017. vacres. 2021; 8 (1) :52-59
URL: http://vacres.pasteur.ac.ir/article-1-275-fa.html
Comparative Study of AEFI of Hepatitis B Vaccine between Iran Ministry of Health CDC and VAERS Data during 2015 to 2017. Vaccine Research. 1400; 8 (1) :59-52

URL: http://vacres.pasteur.ac.ir/article-1-275-fa.html


چکیده:   (247 مشاهده)
Introduction: Hepatitis B Vaccine (HBV) is a safe and effective vaccine that is nowadays recommended for all infants at birth as well as adults who could be exposed to hepatitis B virus. HBV can provide lifetime protection against hepatitis B virus infection. Despite its highly effective disease prevention, HBV can also cause adverse effects for the vaccinated population. A vast majority of Iran's population are vaccinated with recombinant hepatitis B vaccine (rHBV) which is manufactured by the Production and Research Complex of Pasteur Institute of Iran. Methods:  The reported adverse events of rHBV, obtained from Diseases Management Center of Iran’s Ministry of Health were compared with those in The Vaccine Adverse Event Reporting System (VAERS, a United States program for vaccine safety, co-managed by the U.S. Centers for Disease Control and Prevention) during 2015 to 2017. Results: The most common adverse events after administration of rHBV, manufactured by Pasteur Institute of Iran was injection site reactions and no life threatening adverse event was observed. Conclusion: Despite reports by VAERS indicating that HBV can cause adverse events and even death in the United States, no such adverse effects were observed in rHBV manufactured in Iran.
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نوع مطالعه: پژوهشي | موضوع مقاله: Vaccine development, efficacy and safety evaluation
دریافت: 1400/10/13 | پذیرش: 1400/4/9 | انتشار: 1401/1/14

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