دوره 8، شماره 1 - ( 4-1400 )                   جلد 8 شماره 1 صفحات 17-11 | برگشت به فهرست نسخه ها


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Leonova G. Evaluation of the effectiveness of infectious diseases immunoprophylaxis (review of our own research on the model of tick-borne encephalitis). vacres. 2021; 8 (1) :11-17
URL: http://vacres.pasteur.ac.ir/article-1-256-fa.html
Evaluation of the effectiveness of infectious diseases immunoprophylaxis (review of our own research on the model of tick-borne encephalitis). Vaccine Research. 1400; 8 (1) :17-11

URL: http://vacres.pasteur.ac.ir/article-1-256-fa.html


چکیده:   (289 مشاهده)
Introduction: The tick-borne encephalitis (TBE) virus causes a dangerous neuroinfection in humans can serve as a model for studying the mechanisms of interaction of pathogens with specific antibodies during active and passive immunization. Several commercial vaccines are currently used against TBE. This review analyzes long-term studies aimed at explaining the active and passive efficacy of specific immunoprophylaxis against TBE. Methods: The effectiveness of "Encepur® adult" TBE vaccine has been studied in terms of seroconversion and strength of the immune response by serological reactions, namely IFA, ELISA and neutralizing were reviewed. Results: Rapid elimination of the virus (after 1-2 days) can occur in vaccinated individuals with antibodies in titers of more than 1: 400. Persons with antibodies in titers of 1: 100 and 1: 200, most likely, should be offered mandatory revaccination. It should also take into account the duration of the retention of post-vaccination antibodies. Conclusion: In the year of TBE vaccination, the immune response was at a high level and practically did not differ. A particularly high level of immune protection was observed in persons who were vaccinated by a combination of TBE vaccines of various producers.
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نوع مطالعه: Review article | موضوع مقاله: Prophylactic and therapeutic, and plant-based vaccines
دریافت: 1400/5/24 | پذیرش: 1400/3/20 | انتشار: 1400/9/24

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