Volume 7, Issue 1 (6-2020)                   vacres 2020, 7(1): 10-16 | Back to browse issues page


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Department of Biotechnology, School of Life Sciences, Dr. Bhimrao Ambedkar University Agra-282004, UP India
Abstract:   (3217 Views)
Introduction: Coronavirus family member SARS- CoV-2 is a current worldwide threat. It enters into the epithelium membrane of respiratory tract with the help of its antigenic spike proteins and cause Coronavirus disease 2019 (COVID -19). Methods: Considering SARS- CoV-2 a potent vaccine or diagnostic candidate, a bioinformatical study was done to determine its structure homology modeling, physiological properties and structure validation with presence of antigenic sites. Results: The surface glycoprotein of SARS-CoV-2 was found to be a stable protein with stereochemically good structure. It also contains 65 antigenic sites. Conclusion: The present study suggests further wet-lab research to develop a vaccine or diagnostic kit using this promising surface glycoprotein.
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Type of Study: Short communication | Subject: Protein modeling
Received: 2020/03/17

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